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Long-term protective immunity induced by an adjuvant-containing live-attenuated AIDS virus

The use of an adjuvant in vaccination is thought to be effective for enhancing immune responses to various pathogens. We genetically constructed a live attenuated simian human immunodeficiency virus (SHIV) to express the adjuvant molecule Ag85B (SHIV-Ag85B). SHIV-Ag85B could not be detected 4 weeks...

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Detalles Bibliográficos
Autores principales: Okamura, Tomotaka, Shimizu, Yuya, Asaka, Masamitsu N., Kanuma, Tomohiro, Tsujimura, Yusuke, Yamamoto, Takuya, Matsuo, Kazuhiro, Yasutomi, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536741/
https://www.ncbi.nlm.nih.gov/pubmed/34686680
http://dx.doi.org/10.1038/s41541-021-00386-5