Fatty Acids Inhibit LAMP2-Mediated Autophagy Flux via Activating ER Stress Pathway in Alcohol-Related Liver Disease

BACKGROUND & AIMS: Alcohol-related liver disease (ALD) is characterized by accumulation of hepatic free fatty acids (FFAs) and triglyceride (TG)-enriched lipid droplets and cell death. The present study aimed to investigate how FFA or TG induces hepatocyte injury, thereby contributing to the dev...

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Detalles Bibliográficos
Autores principales: Guo, Wei, Zhong, Wei, Hao, Liuyi, Dong, Haibo, Sun, Xinguo, Yue, Ruichao, Li, Tianjiao, Zhou, Zhanxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536789/
https://www.ncbi.nlm.nih.gov/pubmed/34284164
http://dx.doi.org/10.1016/j.jcmgh.2021.07.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536789/
https://www.ncbi.nlm.nih.gov/pubmed/34284164
http://dx.doi.org/10.1016/j.jcmgh.2021.07.002

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