Deorphanization of novel biogenic amine-gated ion channels identifies a new serotonin receptor for learning

Pentameric ligand-gated ion channels (LGICs) play conserved, critical roles in both excitatory and inhibitory synaptic transmission and can be activated by diverse neurochemical ligands. We have performed a characterization of orphan channels from the nematode C. elegans, identifying five new monoam...

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Detalles Bibliográficos
Autores principales: Morud, Julia, Hardege, Iris, Liu, He, Wu, Taihong, Choi, Myung-Kyu, Basu, Swaraj, Zhang, Yun, Schafer, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536830/
https://www.ncbi.nlm.nih.gov/pubmed/34388373
http://dx.doi.org/10.1016/j.cub.2021.07.036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536830/
https://www.ncbi.nlm.nih.gov/pubmed/34388373
http://dx.doi.org/10.1016/j.cub.2021.07.036

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