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Deorphanization of novel biogenic amine-gated ion channels identifies a new serotonin receptor for learning
Pentameric ligand-gated ion channels (LGICs) play conserved, critical roles in both excitatory and inhibitory synaptic transmission and can be activated by diverse neurochemical ligands. We have performed a characterization of orphan channels from the nematode C. elegans, identifying five new monoam...
Autores principales: | Morud, Julia, Hardege, Iris, Liu, He, Wu, Taihong, Choi, Myung-Kyu, Basu, Swaraj, Zhang, Yun, Schafer, William R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536830/ https://www.ncbi.nlm.nih.gov/pubmed/34388373 http://dx.doi.org/10.1016/j.cub.2021.07.036 |
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