Conventional protein kinase C in the brain: repurposing cancer drugs for neurodegenerative treatment?

Protein Kinase C (PKC) isozymes are tightly regulated kinases that transduce a myriad of signals from receptor-mediated hydrolysis of membrane phospholipids. They play an important role in brain physiology, and dysregulation of PKC activity is associated with neurodegeneration. Gain-of-function muta...

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Detalles Bibliográficos
Autores principales: Lordén, Gema, Newton, Alexandra C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536831/
https://www.ncbi.nlm.nih.gov/pubmed/34737895
http://dx.doi.org/10.1042/NS20210036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536831/
https://www.ncbi.nlm.nih.gov/pubmed/34737895
http://dx.doi.org/10.1042/NS20210036

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