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Store-Operated Calcium Channels Contribute to Remifentanil-Induced Postoperative Hyperalgesia via Phosphorylation of CaMKIIα in Rats

PURPOSE: The mechanisms of remifentanil-induced postoperative hyperalgesia (RIPH) remain unclear. Store-operated calcium channels (SOCCs) are mainly comprised of stromal interaction molecules 1 (STIM1) and pore-forming subunits (Orai1). They were found to take a pivotal part in Ca(2+)-dependent proc...

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Detalles Bibliográficos
Autores principales: Zhou, Zhenhui, Mao, Meng, Cai, Xuechun, Zhu, Wei, Sun, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536888/
https://www.ncbi.nlm.nih.gov/pubmed/34703304
http://dx.doi.org/10.2147/JPR.S333297