Enhanced Dissolution of Sildenafil Citrate Using Solid Dispersion with Hydrophilic Polymers: Physicochemical Characterization and In Vivo Sexual Behavior Studies in Male Rats

Sildenafil citrate (SLC) is a frequently used medication (Viagra®) for the treatment of erectile dysfunction (ED). Due to its poor solubility, SLC suffers from a delayed onset of action and poor bioavailability. Hence, the aim of the proposed work was to prepare and evaluate solid dispersions (SDs)...

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Detalles Bibliográficos
Autores principales: Aldawsari, Mohammed F., Anwer, Md. Khalid, Ahmed, Mohammed Muqtader, Fatima, Farhat, Soliman, Gamal A., Bhatia, Saurabh, Zafar, Ameeduzzafar, Aboudzadeh, M. Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536963/
https://www.ncbi.nlm.nih.gov/pubmed/34685271
http://dx.doi.org/10.3390/polym13203512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536963/
https://www.ncbi.nlm.nih.gov/pubmed/34685271
http://dx.doi.org/10.3390/polym13203512

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