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6-Shogaol Antagonizes the Adipocyte-Conditioned Medium-Initiated 5-Fluorouracil Resistance in Human Colorectal Cancer Cells through Controlling the SREBP-1 Level

The resistance of colorectal cancer (CRC) to chemotherapy, e.g., 5-fluorouracil (5-FU), is an impediment to successful cancer treatment. Although many mechanisms have been proposed to explain the occurrence of resistance, little is known concerning the role of the adipocyte-containing microenvironme...

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Detalles Bibliográficos
Autores principales: Lee, Ko-Chao, Wu, Kuen-Lin, Yen, Chia-Kung, Chen, Cheng-Nan, Chang, Shun-Fu, Huang, Wen-Shih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537026/
https://www.ncbi.nlm.nih.gov/pubmed/34685438
http://dx.doi.org/10.3390/life11101067