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Synthesis and Inhibition Activity Study of Triazinyl-Substituted Amino(alkyl)-benzenesulfonamide Conjugates with Polar and Hydrophobic Amino Acids as Inhibitors of Human Carbonic Anhydrases I, II, IV, IX, and XII

Primary sulfonamide derivatives with various heterocycles represent the most widespread group of potential human carbonic anhydrase (hCA) inhibitors with high affinity and selectivity towards specific isozymes from the hCA family. In this work, new 4-aminomethyl- and aminoethyl-benzenesulfonamide de...

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Detalles Bibliográficos
Autores principales: Mikulová, Mária Bodnár, Kružlicová, Dáša, Pecher, Daniel, Petreni, Andrea, Supuran, Claudiu T., Mikuš, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537140/
https://www.ncbi.nlm.nih.gov/pubmed/34681940
http://dx.doi.org/10.3390/ijms222011283