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Discovery of a Novel Class of Norovirus Inhibitors with High Barrier of Resistance

Human noroviruses (HuNoVs) are the most common cause of viral gastroenteritis resulting in ~219,000 deaths annually and a societal cost of ~USD60 billion. There are no antivirals or vaccines available to treat and/or prevent HuNoV. In this study, we performed a large-scale phenotypical antiviral scr...

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Detalles Bibliográficos
Autores principales: Van Dycke, Jana, Puxeddu, Michela, La Regina, Giuseppe, Mastrangelo, Eloise, Tarantino, Delia, Rymenants, Jasper, Sebastiani, Jessica, Nalli, Marianna, Matthijnssens, Jelle, Neyts, Johan, Silvestri, Romano, Rocha-Pereira, Joana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537218/
https://www.ncbi.nlm.nih.gov/pubmed/34681230
http://dx.doi.org/10.3390/ph14101006