Effect of Ivermectin and Atorvastatin on Nuclear Localization of Importin Alpha and Drug Target Expression Profiling in Host Cells from Nasopharyngeal Swabs of SARS-CoV-2- Positive Patients

Nuclear transport and vesicle trafficking are key cellular functions involved in the pathogenesis of RNA viruses. Among other pleiotropic effects on virus-infected host cells, ivermectin (IVM) inhibits nuclear transport mechanisms mediated by importins and atorvastatin (ATV) affects actin cytoskelet...

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Detalles Bibliográficos
Autores principales: Segatori, Valeria Inés, Garona, Juan, Caligiuri, Lorena Grisel, Bizzotto, Juan, Lavignolle, Rosario, Toro, Ayelén, Sanchis, Pablo, Spitzer, Eduardo, Krolewiecki, Alejandro, Gueron, Geraldine, Alonso, Daniel Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537229/
https://www.ncbi.nlm.nih.gov/pubmed/34696514
http://dx.doi.org/10.3390/v13102084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537229/
https://www.ncbi.nlm.nih.gov/pubmed/34696514
http://dx.doi.org/10.3390/v13102084

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