Dose- and Sex-Dependent Changes in Hemoglobin Oxygen Affinity by the Micronutrient 5-Hydroxymethylfurfural and α-Ketoglutaric Acid

5-Hydroxymethylfurfural (5-HMF) is known to increase hemoglobin oxygen affinity (Hb–O(2) affinity) and to induce a left shift of the oxygen dissociation curve (ODC). It is under investigation as a therapeutic agent in sickle cell anemia and in conditions where pulmonary oxygen uptake is deteriorated...

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Detalles Bibliográficos
Autores principales: Woyke, Simon, Mair, Norbert, Ortner, Astrid, Haller, Thomas, Ronzani, Marco, Rugg, Christopher, Ströhle, Mathias, Wintersteiger, Reinhold, Gatterer, Hannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537252/
https://www.ncbi.nlm.nih.gov/pubmed/34684449
http://dx.doi.org/10.3390/nu13103448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537252/
https://www.ncbi.nlm.nih.gov/pubmed/34684449
http://dx.doi.org/10.3390/nu13103448

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