Pharmacokinetic/Pharmacodynamic Model of Neutropenia in Real-Life Palbociclib-Treated Patients

Palbociclib is an oral CDK4/6 inhibitor indicated in HR+/HER2- advanced or metastatic breast cancer in combination with hormonotherapy. Its main toxicity is neutropenia. The aim of our study was to describe the kinetics of circulating neutrophils from real-life palbociclib-treated patients. A popula...

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Detalles Bibliográficos
Autores principales: Marouille, Alexandre Le, Petit, Emma, Kaderbhaï, Courèche, Desmoulins, Isabelle, Hennequin, Audrey, Mayeur, Didier, Fumet, Jean-David, Ladoire, Sylvain, Tharin, Zoé, Ayati, Siavoshe, Ilie, Silvia, Royer, Bernard, Schmitt, Antonin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537267/
https://www.ncbi.nlm.nih.gov/pubmed/34684001
http://dx.doi.org/10.3390/pharmaceutics13101708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537267/
https://www.ncbi.nlm.nih.gov/pubmed/34684001
http://dx.doi.org/10.3390/pharmaceutics13101708

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