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Improving the Antitumor Activity and Bioavailability of Sonidegib for the Treatment of Skin Cancer

Throughout the United States and the world, skin cancer is the most frequent form of cancer. Sonidegib (SNG) is a hedgehog inhibitor that has been used for skin cancer treatment. However, SNG has low bioavailability and is associated with resistance. The focus of this work is to enhance bioavailabil...

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Detalles Bibliográficos
Autores principales: Gamal, Amr, Saeed, Haitham, El-Ela, Fatma I. Abo, Salem, Heba F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537379/
https://www.ncbi.nlm.nih.gov/pubmed/34683853
http://dx.doi.org/10.3390/pharmaceutics13101560