Design, Microwave-Assisted Synthesis and In Silico Prediction Study of Novel Isoxazole Linked Pyranopyrimidinone Conjugates as New Targets for Searching Potential Anti-SARS-CoV-2 Agents

A series of novel naphthopyrano[2,3-d]pyrimidin-11(12H)-one containing isoxazole nucleus 4 was synthesized under microwave irradiation and classical conditions in moderate to excellent yields upon 1,3-dipolar cycloaddition reaction using various arylnitrile oxides under copper(I) catalyst. A one-pot...

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Detalles Bibliográficos
Autores principales: Algethami, Faisal K., Cherif, Maher, Jlizi, Salma, Ben Hamadi, Naoufel, Romdhane, Anis, Elamin, Mohamed R., Alghamdi, Mashael A., Ben Jannet, Hichem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537412/
https://www.ncbi.nlm.nih.gov/pubmed/34684683
http://dx.doi.org/10.3390/molecules26206103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537412/
https://www.ncbi.nlm.nih.gov/pubmed/34684683
http://dx.doi.org/10.3390/molecules26206103

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