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Optimization of Synthesis of the Amino Lipid ECO for Effective Delivery of Nucleic Acids

Nucleic acids are promising for a variety of therapies, such as cancer therapy and the gene therapy of genetic disorders. The therapeutic efficacy of nucleic acids is reliant on the ability of their efficient delivery to the cytosol of the target cells. Amino lipids have been developed to aid in the...

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Detalles Bibliográficos
Autores principales: Schilb, Andrew L., Scheidt, Josef H., Vaidya, Amita M., Sun, Zhanhu, Sun, Da, Lee, Sangjoon, Lu, Zheng-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537419/
https://www.ncbi.nlm.nih.gov/pubmed/34681240
http://dx.doi.org/10.3390/ph14101016