Population Pharmacokinetic Modelling of the Complex Release Kinetics of Octreotide LAR: Defining Sub-Populations by Cluster Analysis

The aim of the study is to develop a population pharmacokinetic (PPK) model, of Octreotide long acting repeatable (LAR) formulation in healthy volunteers, which describes the highly variable, multiple peak absorption pattern of the pharmacokinetics of the drug, in individual and population levels. A...

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Detalles Bibliográficos
Autores principales: Kapralos, Iasonas, Dokoumetzidis, Aristides
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537465/
https://www.ncbi.nlm.nih.gov/pubmed/34683871
http://dx.doi.org/10.3390/pharmaceutics13101578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537465/
https://www.ncbi.nlm.nih.gov/pubmed/34683871
http://dx.doi.org/10.3390/pharmaceutics13101578

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