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Extracellular Vesicles from Human Teeth Stem Cells Trigger ATP Release and Promote Migration of Human Microglia through P2X4 Receptor/MFG-E8-Dependent Mechanisms

Extracellular vesicles (EVs) effectively suppress neuroinflammation and induce neuroprotective effects in different disease models. However, the mechanisms by which EVs regulate the neuroinflammatory response of microglia remains largely unexplored. Here, we addressed this issue by testing the actio...

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Detalles Bibliográficos
Autores principales: Jonavičė, Ugnė, Romenskaja, Diana, Kriaučiūnaitė, Karolina, Jarmalavičiūtė, Akvilė, Pajarskienė, Justina, Kašėta, Vytautas, Tunaitis, Virginijus, Malm, Tarja, Giniatulin, Rashid, Pivoriūnas, Augustas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537493/
https://www.ncbi.nlm.nih.gov/pubmed/34681627
http://dx.doi.org/10.3390/ijms222010970