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Identification of Effective Anticancer G-Quadruplex-Targeting Chemotypes through the Exploration of a High Diversity Library of Natural Compounds

In the quest for selective G-quadruplex (G4)-targeting chemotypes, natural compounds have been thus far poorly explored, though representing appealing candidates due to the high structural diversity of their scaffolds. In this regard, a unique high diversity in-house library composed of ca. one thou...

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Detalles Bibliográficos
Autores principales: Platella, Chiara, Ghirga, Francesca, Zizza, Pasquale, Pompili, Luca, Marzano, Simona, Pagano, Bruno, Quaglio, Deborah, Vergine, Valeria, Cammarone, Silvia, Botta, Bruno, Biroccio, Annamaria, Mori, Mattia, Montesarchio, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537501/
https://www.ncbi.nlm.nih.gov/pubmed/34683905
http://dx.doi.org/10.3390/pharmaceutics13101611