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Interaction between NS1 and Cellular MAVS Contributes to NS1 Mitochondria Targeting

Influenza A virus nonstructural protein 1 (NS1) plays an important role in evading host innate immunity. NS1 inhibits interferon (IFN) responses via multiple mechanisms, including sequestering dsRNA and suppressing retinoic acid-inducible gene I (RIG-I) signaling by interacting with RIG-I and tripar...

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Detalles Bibliográficos
Autores principales: Tseng, Yeu-Yang, Kuan, Chih-Ying, Mibayashi, Masaki, Chen, Chi-Jene, Palese, Peter, Albrecht, Randy A., Hsu, Wei-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537625/
https://www.ncbi.nlm.nih.gov/pubmed/34696339
http://dx.doi.org/10.3390/v13101909