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A Drug Repurposing Approach for Antimalarials Interfering with SARS-CoV-2 Spike Protein Receptor Binding Domain (RBD) and Human Angiotensin-Converting Enzyme 2 (ACE2)

Host cell invasion by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is mediated by the interaction of the viral spike protein (S) with human angiotensin-converting enzyme 2 (ACE2) through the receptor-binding domain (RBD). In this work, computational and experimental techniques were c...

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Detalles Bibliográficos
Autores principales: Coghi, Paolo, Yang, Li Jun, Ng, Jerome P. L., Haynes, Richard K., Memo, Maurizio, Gianoncelli, Alessandra, Wong, Vincent Kam Wai, Ribaudo, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537658/
https://www.ncbi.nlm.nih.gov/pubmed/34681178
http://dx.doi.org/10.3390/ph14100954