Polygodial and Ophiobolin A Analogues for Covalent Crosslinking of Anticancer Targets

In a search of small molecules active against apoptosis-resistant cancer cells, including glioma, melanoma, and non-small cell lung cancer, we previously prepared α,β- and γ,δ-unsaturated ester analogues of polygodial and ophiobolin A, compounds capable of pyrrolylation of primary amines and demonst...

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Detalles Bibliográficos
Autores principales: Maslivetc, Vladimir, Laguera, Breana, Chandra, Sunena, Dasari, Ramesh, Olivier, Wesley J., Smith, Jason A., Bissember, Alex C., Masi, Marco, Evidente, Antonio, Mathieu, Veronique, Kornienko, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537666/
https://www.ncbi.nlm.nih.gov/pubmed/34681916
http://dx.doi.org/10.3390/ijms222011256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537666/
https://www.ncbi.nlm.nih.gov/pubmed/34681916
http://dx.doi.org/10.3390/ijms222011256

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