Mechanistic Understanding from Molecular Dynamics in Pharmaceutical Research 2: Lipid Membrane in Drug Design

We review the use of molecular dynamics (MD) simulation as a drug design tool in the context of the role that the lipid membrane can play in drug action, i.e., the interaction between candidate drug molecules and lipid membranes. In the standard “lock and key” paradigm, only the interaction between...

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Detalles Bibliográficos
Autores principales: Róg, Tomasz, Girych, Mykhailo, Bunker, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537670/
https://www.ncbi.nlm.nih.gov/pubmed/34681286
http://dx.doi.org/10.3390/ph14101062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537670/
https://www.ncbi.nlm.nih.gov/pubmed/34681286
http://dx.doi.org/10.3390/ph14101062

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