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Primary Human Hepatocyte Spheroids as Tools to Study the Hepatotoxic Potential of Non-Pharmaceutical Chemicals

Drug-induced liver injury, including cholestasis, is an important clinical issue and economic burden for pharmaceutical industry and healthcare systems. However, human-relevant in vitro information on the ability of other types of chemicals to induce cholestatic hepatotoxicity is lacking. This work...

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Detalles Bibliográficos
Autores principales: Vilas-Boas, Vânia, Gijbels, Eva, Leroy, Kaat, Pieters, Alanah, Baze, Audrey, Parmentier, Céline, Vinken, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537720/
https://www.ncbi.nlm.nih.gov/pubmed/34681664
http://dx.doi.org/10.3390/ijms222011005