Cargando…
Primary Human Hepatocyte Spheroids as Tools to Study the Hepatotoxic Potential of Non-Pharmaceutical Chemicals
Drug-induced liver injury, including cholestasis, is an important clinical issue and economic burden for pharmaceutical industry and healthcare systems. However, human-relevant in vitro information on the ability of other types of chemicals to induce cholestatic hepatotoxicity is lacking. This work...
Autores principales: | Vilas-Boas, Vânia, Gijbels, Eva, Leroy, Kaat, Pieters, Alanah, Baze, Audrey, Parmentier, Céline, Vinken, Mathieu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537720/ https://www.ncbi.nlm.nih.gov/pubmed/34681664 http://dx.doi.org/10.3390/ijms222011005 |
Ejemplares similares
-
Connexin-Based Channel Activity Is Not Specifically Altered by Hepatocarcinogenic Chemicals
por: Leroy, Kaat, et al.
Publicado: (2021) -
In Vitro Liver Toxicity Testing of Chemicals: A Pragmatic Approach
por: Tabernilla, Andrés, et al.
Publicado: (2021) -
Expression of connexins and pannexins in diseased human liver
por: Leroy, Kaat, et al.
Publicado: (2022) -
Rodent models of cholestatic liver disease: A practical guide for translational research
por: Gijbels, Eva, et al.
Publicado: (2021) -
Increased Expression of Adherens Junction Components in Mouse Liver following Bile Duct Ligation
por: Van Campenhout, Raf, et al.
Publicado: (2019)