Induction of Endoplasmic Reticulum Stress-Mediated Apoptosis by Aminosteroid RM-581 Efficiently Blocks the Growth of PC-3 Cancer Cells and Tumors Resistant or Not to Docetaxel

Aminosteroid derivative RM-581 was previously identified as an endoplasmic-reticulum (ER) stress inducer with potent in vitro and in vivo anticancer activities. We report its evaluation in androgen-independent prostate cancer (PC-3) cells. RM-581 efficiently blocks PC-3 cell proliferation with stron...

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Detalles Bibliográficos
Autores principales: Maltais, René, Roy, Jenny, Perreault, Martin, Sato, Sachiko, Lévesque, Julie-Christine, Poirier, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537847/
https://www.ncbi.nlm.nih.gov/pubmed/34681843
http://dx.doi.org/10.3390/ijms222011181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537847/
https://www.ncbi.nlm.nih.gov/pubmed/34681843
http://dx.doi.org/10.3390/ijms222011181

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