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Precursors of Viral Proteases as Distinct Drug Targets

Viral proteases are indispensable for successful virion maturation, thus making them a prominent drug target. Their enzyme activity is tightly spatiotemporally regulated by expression in the precursor form with little or no activity, followed by activation via autoprocessing. These cleavage events a...

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Detalles Bibliográficos
Autores principales: Majerová, Taťána, Novotný, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537868/
https://www.ncbi.nlm.nih.gov/pubmed/34696411
http://dx.doi.org/10.3390/v13101981