Cargando…

SOD2 Enhancement by Long-Term Inhibition of the PI3K Pathway Confers Multi-Drug Resistance and Enhanced Tumor-Initiating Features in Head and Neck Cancer

The phosphoinositide-3-kinase (PI3K) pathway has widely been considered as a potential therapeutic target for head and neck cancer (HNC); however, the application of PI3K inhibitors is often overshadowed by the induction of drug resistance with unknown mechanisms. In this study, PII3K inhibitor resi...

Descripción completa

Detalles Bibliográficos
Autores principales: Hsueh, Wei-Ting, Chen, Shang-Hung, Chien, Chia-Hung, Chou, Shao-Wen, Chi, Pei-I, Chu, Jui-Mei, Chang, Kwang-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537886/
https://www.ncbi.nlm.nih.gov/pubmed/34681918
http://dx.doi.org/10.3390/ijms222011260