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SOD2 Enhancement by Long-Term Inhibition of the PI3K Pathway Confers Multi-Drug Resistance and Enhanced Tumor-Initiating Features in Head and Neck Cancer
The phosphoinositide-3-kinase (PI3K) pathway has widely been considered as a potential therapeutic target for head and neck cancer (HNC); however, the application of PI3K inhibitors is often overshadowed by the induction of drug resistance with unknown mechanisms. In this study, PII3K inhibitor resi...
Autores principales: | Hsueh, Wei-Ting, Chen, Shang-Hung, Chien, Chia-Hung, Chou, Shao-Wen, Chi, Pei-I, Chu, Jui-Mei, Chang, Kwang-Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537886/ https://www.ncbi.nlm.nih.gov/pubmed/34681918 http://dx.doi.org/10.3390/ijms222011260 |
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