Endothelial Thioredoxin-Interacting Protein Depletion Reduces Hemorrhagic Transformation in Hyperglycemic Mice after Embolic Stroke and Thrombolytic Therapy

We hypothesize that endothelial-specific thioredoxin-interacting protein knock-out (EC-TXNIP KO) mice will be more resistant to the neurovascular damage (hemorrhagic-transformation-HT) associated with hyperglycemia (HG) in embolic stroke. Adult-male EC-TXNIP KO and wild-type (WT) littermate mice wer...

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Detalles Bibliográficos
Autores principales: Salman, Mohd., Ismael, Saifudeen, Li, Lexiao, Ahmed, Heba A., Puchowicz, Michelle A., Ishrat, Tauheed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537904/
https://www.ncbi.nlm.nih.gov/pubmed/34681207
http://dx.doi.org/10.3390/ph14100983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537904/
https://www.ncbi.nlm.nih.gov/pubmed/34681207
http://dx.doi.org/10.3390/ph14100983

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