Resistomycin Induced Apoptosis and Cycle Arrest in Human Hepatocellular Carcinoma Cells by Activating p38 MAPK Pathway In Vitro and In Vivo

Resistomycin, a quinone-related natural antibiotic, has shown strong inhibitory activity against human hepatocellular carcinoma (HCC) in vitro. Here, we investigated the role of p38 MAPK in the pro-apoptotic and G2/M phase arrest action of HCC HepG2 cells upon treatment with resistomycin in vitro an...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Zhuo, Zhao, Xingming, Zhang, E, Ma, Jiahui, Zhang, Hao, Li, Jianjiang, Xie, Weidong, Li, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537932/
https://www.ncbi.nlm.nih.gov/pubmed/34681182
http://dx.doi.org/10.3390/ph14100958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537932/
https://www.ncbi.nlm.nih.gov/pubmed/34681182
http://dx.doi.org/10.3390/ph14100958

Ejemplares similares