Multi-Omics Approach to Mitochondrial DNA Damage in Human Muscle Fibers

Mitochondrial DNA deletions affect energy metabolism at tissue-specific and cell-specific threshold levels, but the pathophysiological mechanisms determining cell fate remain poorly understood. Chronic progressive external ophthalmoplegia (CPEO) is caused by mtDNA deletions and characterized by a mo...

Descripción completa

Detalles Bibliográficos
Autores principales: Elstner, Matthias, Olszewski, Konrad, Prokisch, Holger, Klopstock, Thomas, Murgia, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537949/
https://www.ncbi.nlm.nih.gov/pubmed/34681740
http://dx.doi.org/10.3390/ijms222011080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537949/
https://www.ncbi.nlm.nih.gov/pubmed/34681740
http://dx.doi.org/10.3390/ijms222011080

Ejemplares similares