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Multi-Omics Approach to Mitochondrial DNA Damage in Human Muscle Fibers

Mitochondrial DNA deletions affect energy metabolism at tissue-specific and cell-specific threshold levels, but the pathophysiological mechanisms determining cell fate remain poorly understood. Chronic progressive external ophthalmoplegia (CPEO) is caused by mtDNA deletions and characterized by a mo...

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Detalles Bibliográficos
Autores principales:	Elstner, Matthias, Olszewski, Konrad, Prokisch, Holger, Klopstock, Thomas, Murgia, Marta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537949/ https://www.ncbi.nlm.nih.gov/pubmed/34681740 http://dx.doi.org/10.3390/ijms222011080

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