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IFNα and β Mediated JCPyV Suppression through C/EBPβ-LIP Isoform

Polyomavirus JC (JCPyV) causes the demyelinating disease progressive multifocal leukoencephalopathy (PML). JCPyV infection is very common in childhood and, under conditions of severe immunosuppression, JCPyV may reactivate to cause PML. JC viral proteins expression is regulated by the JCPyV non-codi...

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Detalles Bibliográficos
Autores principales: May, Dana, Bellizzi, Anna, Kassa, Workineh, Cipriaso, John M., Caocci, Maurizio, Wollebo, Hassen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537971/
https://www.ncbi.nlm.nih.gov/pubmed/34696366
http://dx.doi.org/10.3390/v13101937