Synthesis of Halogenated 1,5-Diarylimidazoles and Their Inhibitory Effects on LPS-Induced PGE(2) Production in RAW 264.7 Cells

A series of halogenated 1,5-diarylimidazole compounds were synthesized and their inhibitory effects on LPS-induced PGE(2) production in RAW 264.7 cells were evaluated. A wide variety of 2,4-, 4-, and 2-halogenated 5-aryl-1-(4-methylsulfonylphenyl)imidazoles were synthesized for SAR study via two dif...

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Detalles Bibliográficos
Autores principales: Yang, Zunhua, Fang, Yuanying, Kim, Jae-Min, Lee, Kyung-Tae, Park, Haeil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538130/
https://www.ncbi.nlm.nih.gov/pubmed/34684673
http://dx.doi.org/10.3390/molecules26206093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538130/
https://www.ncbi.nlm.nih.gov/pubmed/34684673
http://dx.doi.org/10.3390/molecules26206093

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