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Constant Voltage Iontophoresis Technique to Deliver Terbinafine via Transungual Delivery System: Formulation Optimization Using Box–Behnken Design and In Vitro Evaluation

Topical therapy of antifungals is primarily restricted due to the low innate transport of drugs through the thick multi-layered keratinized nail plate. The objective of this investigation was to develop a gel formulation, and to optimize and evaluate the transungual delivery of terbinafine using the...

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Detalles Bibliográficos
Autores principales: Nair, Anroop B., Al-Dhubiab, Bandar E., Shah, Jigar, Gorain, Bapi, Jacob, Shery, Attimarad, Mahesh, Sreeharsha, Nagaraja, Venugopala, Katharigatta N., Morsy, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538220/
https://www.ncbi.nlm.nih.gov/pubmed/34683985
http://dx.doi.org/10.3390/pharmaceutics13101692