The Role of Nrf2 Transcription Factor and Sp1-Nrf2 Protein Complex in Glutamine Transporter SN1 Regulation in Mouse Cortical Astrocytes Exposed to Ammonia

Ammonia toxicity in the brain primarily affects astrocytes via a mechanism in which oxidative stress (OS), is coupled to the imbalance between glutamatergic and GABAergic transmission. Ammonia also downregulates the astrocytic N system transporter SN1 that controls glutamine supply from astrocytes t...

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Detalles Bibliográficos
Autores principales: Dąbrowska, Katarzyna, Skowrońska, Katarzyna, Popek, Mariusz, Albrecht, Jan, Zielińska, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538223/
https://www.ncbi.nlm.nih.gov/pubmed/34681893
http://dx.doi.org/10.3390/ijms222011233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538223/
https://www.ncbi.nlm.nih.gov/pubmed/34681893
http://dx.doi.org/10.3390/ijms222011233

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