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The Role of Nrf2 Transcription Factor and Sp1-Nrf2 Protein Complex in Glutamine Transporter SN1 Regulation in Mouse Cortical Astrocytes Exposed to Ammonia
Ammonia toxicity in the brain primarily affects astrocytes via a mechanism in which oxidative stress (OS), is coupled to the imbalance between glutamatergic and GABAergic transmission. Ammonia also downregulates the astrocytic N system transporter SN1 that controls glutamine supply from astrocytes t...
Autores principales: | Dąbrowska, Katarzyna, Skowrońska, Katarzyna, Popek, Mariusz, Albrecht, Jan, Zielińska, Magdalena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538223/ https://www.ncbi.nlm.nih.gov/pubmed/34681893 http://dx.doi.org/10.3390/ijms222011233 |
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