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Point Mutations in the Glycoprotein Ectodomain of Field Rabies Viruses Mediate Cell Culture Adaptation through Improved Virus Release in a Host Cell Dependent and Independent Manner

Molecular details of field rabies virus (RABV) adaptation to cell culture replication are insufficiently understood. A better understanding of adaptation may not only reveal requirements for efficient RABV replication in cell lines, but may also provide novel insights into RABV biology and adaptatio...

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Detalles Bibliográficos
Autores principales: Nitschel, Sabine, Zaeck, Luca M., Potratz, Madlin, Nolden, Tobias, te Kamp, Verena, Franzke, Kati, Höper, Dirk, Pfaff, Florian, Finke, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538267/
https://www.ncbi.nlm.nih.gov/pubmed/34696419
http://dx.doi.org/10.3390/v13101989