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Point Mutations in the Glycoprotein Ectodomain of Field Rabies Viruses Mediate Cell Culture Adaptation through Improved Virus Release in a Host Cell Dependent and Independent Manner
Molecular details of field rabies virus (RABV) adaptation to cell culture replication are insufficiently understood. A better understanding of adaptation may not only reveal requirements for efficient RABV replication in cell lines, but may also provide novel insights into RABV biology and adaptatio...
Autores principales: | Nitschel, Sabine, Zaeck, Luca M., Potratz, Madlin, Nolden, Tobias, te Kamp, Verena, Franzke, Kati, Höper, Dirk, Pfaff, Florian, Finke, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538267/ https://www.ncbi.nlm.nih.gov/pubmed/34696419 http://dx.doi.org/10.3390/v13101989 |
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