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Engineering Pyrrolysyl-tRNA Synthetase for the Incorporation of Non-Canonical Amino Acids with Smaller Side Chains

Site-specific incorporation of non-canonical amino acids (ncAAs) into proteins has emerged as a universal tool for systems bioengineering at the interface of chemistry, biology, and technology. The diversification of the repertoire of the genetic code has been achieved for amino acids with long and/...

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Detalles Bibliográficos
Autores principales: Koch, Nikolaj G., Goettig, Peter, Rappsilber, Juri, Budisa, Nediljko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538471/
https://www.ncbi.nlm.nih.gov/pubmed/34681855
http://dx.doi.org/10.3390/ijms222011194