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Atorvastatin Ester Regulates Lipid Metabolism in Hyperlipidemia Rats via the PPAR-signaling Pathway and HMGCR Expression in the Liver

Atorvastatin ester (Ate) is a structural trim of atorvastatin that can regulate hyperlipidemia. The purpose of this study was to evaluate the lipid-lowering effect of Ate. Male Sprague Dawley (SD) rats were fed a high-fat diet for seven months and used as a hyperlipidemia model. The lipid level and...

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Detalles Bibliográficos
Autores principales: Hu, Nan, Chen, Chunyun, Wang, Jinhui, Huang, Jian, Yao, Dahong, Li, Chunli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538474/
https://www.ncbi.nlm.nih.gov/pubmed/34681767
http://dx.doi.org/10.3390/ijms222011107