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Kidney and Liver Tissue Tacrolimus Concentrations in Adult Transplant Recipients—The Influence of the Whole Blood and Tissue Concentrations on Efficiency of Treatment during Immunosuppressive Therapy

Tacrolimus (TAC) has a narrow therapeutic index and highly variable pharmacokinetic characteristics. Close monitoring of the TAC concentrations is required in order to avoid the risk of acute rejection or adverse drug reaction. The results in some studies indicate that inter-tissue TAC concentration...

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Detalles Bibliográficos
Autores principales: Bodnar-Broniarczyk, Magdalena, Durlik, Magdalena, Bączkowska, Teresa, Czerwińska, Katarzyna, Marszałek, Ryszard, Pawiński, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538499/
https://www.ncbi.nlm.nih.gov/pubmed/34683869
http://dx.doi.org/10.3390/pharmaceutics13101576