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Deregulation of N6-Methyladenosine RNA Modification and Its Erasers FTO/ALKBH5 among the Main Renal Cell Tumor Subtypes

(1) Background: Methylation of N(6)-adenosine (m(6)A) is the most abundant messenger RNA (mRNA) modification in eukaryotes. We assessed the expression profiles of m(6)A regulatory proteins in renal cell carcinoma (RCC) and their clinical relevance, namely, as potential biomarkers. (2) Methods: In si...

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Detalles Bibliográficos
Autores principales: Guimarães-Teixeira, Catarina, Barros-Silva, Daniela, Lobo, João, Soares-Fernandes, Diana, Constâncio, Vera, Leite-Silva, Pedro, Silva-Santos, Rui, Braga, Isaac, Henrique, Rui, Miranda-Gonçalves, Vera, Jerónimo, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538585/
https://www.ncbi.nlm.nih.gov/pubmed/34683137
http://dx.doi.org/10.3390/jpm11100996