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Bee Venom Melittin Disintegrates the Respiration of Mitochondria in Healthy Cells and Lymphoblasts, and Induces the Formation of Non-Bilayer Structures in Model Inner Mitochondrial Membranes

In this paper, we examined the effects of melittin, a bee venom membrane-active peptide, on mitochondrial respiration and cell viability of healthy human lymphocytes (HHL) and Jurkat cells, as well as on lymphoblasts from acute human T cell leukemia. The viability of melittin-treated cells was relat...

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Detalles Bibliográficos
Autores principales: Gasanoff, Edward, Liu, Yipeng, Li, Feng, Hanlon, Paul, Garab, Győző
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538590/
https://www.ncbi.nlm.nih.gov/pubmed/34681781
http://dx.doi.org/10.3390/ijms222011122