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Synthesis and Biological Application of Isosteviol-Based 1,3-Aminoalcohols

Starting from isosteviol, a series of diterpenoid 1,3-aminoalcohol derivatives were stereoselectively synthesised. The acid-catalysed hydrolysis and rearrangement of natural stevioside gave isosteviol, which was transformed to the key intermediate methyl ester. In the next step, Mannich condensation...

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Detalles Bibliográficos
Autores principales: Ozsvár, Dániel, Nagy, Viktória, Zupkó, István, Szakonyi, Zsolt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538607/
https://www.ncbi.nlm.nih.gov/pubmed/34681892
http://dx.doi.org/10.3390/ijms222011232