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Application of Photodynamic Therapy with 5-Aminolevulinic Acid to Extracorporeal Photopheresis in the Treatment of Patients with Chronic Graft-versus-Host Disease: A First-in-Human Study

Extracorporeal photopheresis (ECP), an immunomodulatory therapy for the treatment of chronic graft-versus-host disease (cGvHD), exposes isolated white blood cells to photoactivatable 8-methoxypsoralen (8-MOP) and UVA light to induce the apoptosis of T-cells and, hence, to modulate immune responses....

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Detalles Bibliográficos
Autores principales: Christensen, Eidi, Foss, Olav A., Quist-Paulsen, Petter, Staur, Ingrid, Pettersen, Frode, Holien, Toril, Juzenas, Petras, Peng, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538664/
https://www.ncbi.nlm.nih.gov/pubmed/34683851
http://dx.doi.org/10.3390/pharmaceutics13101558