Design and Evaluation of Losartan Potassium Effervescent Floating Matrix Tablets: In Vivo X-ray Imaging and Pharmacokinetic Studies in Albino Rabbits

Losartan potassium (LP) is an angiotensin receptor blocker used to treat hypertension. At higher pH, it shows poor aqueous solubility, which leads to poor bioavailability and lowers its therapeutic effectiveness. The main aim of this research was to develop a direct compressed effervescent floating...

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Detalles Bibliográficos
Autores principales: Rahamathulla, Mohamed, Saisivam, Srinivasan, Alshetaili, Abdullah, Hani, Umme, Gangadharappa, Hosahalli Veerabhadrappa, Alshehri, Sultan, Ghoneim, Mohammed M., Shakeel, Faiyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538939/
https://www.ncbi.nlm.nih.gov/pubmed/34685235
http://dx.doi.org/10.3390/polym13203476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538939/
https://www.ncbi.nlm.nih.gov/pubmed/34685235
http://dx.doi.org/10.3390/polym13203476

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