Cargando…

Design and Evaluation of Losartan Potassium Effervescent Floating Matrix Tablets: In Vivo X-ray Imaging and Pharmacokinetic Studies in Albino Rabbits

Losartan potassium (LP) is an angiotensin receptor blocker used to treat hypertension. At higher pH, it shows poor aqueous solubility, which leads to poor bioavailability and lowers its therapeutic effectiveness. The main aim of this research was to develop a direct compressed effervescent floating...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rahamathulla, Mohamed, Saisivam, Srinivasan, Alshetaili, Abdullah, Hani, Umme, Gangadharappa, Hosahalli Veerabhadrappa, Alshehri, Sultan, Ghoneim, Mohammed M., Shakeel, Faiyaz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538939/ https://www.ncbi.nlm.nih.gov/pubmed/34685235 http://dx.doi.org/10.3390/polym13203476

Ejemplares similares

Carbon Nanotubes: Current Perspectives on Diverse Applications in Targeted Drug Delivery and Therapies
por: Rahamathulla, Mohamed, et al.
Publicado: (2021)

Preparation, Characterization and Evaluation of Flavonolignan Silymarin Effervescent Floating Matrix Tablets for Enhanced Oral Bioavailability
por: Ahmad, Sher, et al.
Publicado: (2023)

Effect of bioadhesion on initial in vitro buoyancy of effervescent floating matrix tablets of ciprofloxacin HCL
por: Negi, Jeetendra Singh, et al.
Publicado: (2011)

Formulation and In Vitro, In Vivo Evaluation of Effervescent Floating Sustained-Release Imatinib Mesylate Tablet
por: Kadivar, Ali, et al.
Publicado: (2015)

Design and In-vitro Evaluation of Sustained Release Floating Tablets of Metformin HCl Based on Effervescence and Swelling
por: Senjoti, Faria Gias, et al.
Publicado: (2016)

Correction: Formulation and In Vitro, In Vivo Evaluation of Effervescent Floating Sustained-Release Imatinib Mesylate Tablet
Publicado: (2022)

Hydrochlorothiazide/Losartan Potassium Tablet Prepared by Direct Compression
por: Luo, Qiuhua, et al.
Publicado: (2022)

Investigating Antiarthritic Potential of Nanostructured Clove Oil (Syzygium aromaticum) in FCA-Induced Arthritic Rats: Pharmaceutical Action and Delivery Strategies
por: Shakeel, Faiyaz, et al.
Publicado: (2021)

Sustained-release effervescent floating matrix tablets of baclofen: development, optimization and in vitro-in vivo evaluation in healthy human volunteers
por: Gande, S, et al.
Publicado: (2011)

Design and evaluation of effervescent floating tablets based on hydroxyethyl cellulose and sodium alginate using pentoxifylline as a model drug
por: Rahim, Safwan Abdel, et al.
Publicado: (2015)

Formulation and Characterization of an Effervescent Hydrogen-Generating Tablet
por: Rosch, Moritz, et al.
Publicado: (2021)

Newfangled Topical Film-Forming Solution for Facilitated Antifungal Therapy: Design, Development, Characterization, and In Vitro Evaluation
por: Dhimmar, Bhakti, et al.
Publicado: (2023)

Design and In Vitro Evaluation of Compression-coated Pulsatile Release Tablets of Losartan Potassium
por: Bajpai, M., et al.
Publicado: (2012)

Development and evaluation of chitosan based oral controlled matrix tablets of losartan potassium
por: Rao, Tallapaneni Vishnuvardhan, et al.
Publicado: (2012)

Human Bioequivalence Evaluation of Two Losartan Potassium Tablets Under Fasting Conditions
por: Das, A. K., et al.
Publicado: (2015)

Pharmaceutical Development of Film-Coated Mini-Tablets with Losartan Potassium for Epidermolysis Bullosa
por: Elezaj, Valentinë, et al.
Publicado: (2022)

Fast Dissolving Tablets of Fexofenadine HCl by Effervescent Method
por: Nagendrakumar, D., et al.
Publicado: (2009)

Formulation, characterization and physicochemical evaluation of amoxicillin effervescent tablets
por: Aslani, Abolfazl, et al.
Publicado: (2014)

Spectrophotometric and HPLC Methods for Simultaneous Estimation of Amlodipine Besilate, Losartan Potassium and Hydrochlorothiazide in Tablets
por: Wankhede, S. B., et al.
Publicado: (2010)

Hepatoprotective Effects of Bioflavonoid Luteolin Using Self-Nanoemulsifying Drug Delivery System
por: Shakeel, Faiyaz, et al.
Publicado: (2021)

Design of Fast Disintegrating Tablets of Prochlorperazine Maleate by Effervescence Method
por: Shirsand, S. B., et al.
Publicado: (2009)

Preparation and Evaluation of Orodispersible Tablets of Pheniramine Maleate by Effervescent Method
por: Swamy, P. V., et al.
Publicado: (2009)

A Method for Content Uniformity Determination of Atenolol and Losartan Potassium in Combined Tablet Dosage Form
por: Shah, S. A., et al.
Publicado: (2010)

Spectrophotometric method for simultaneous estimation of atenolol in combination with losartan potassium and hydrochlorothiazide in bulk and tablet formulation
por: Bari, Sanjay, et al.
Publicado: (2010)

Meta-analysis of the effectiveness and safety of Shenyankangfu tablets combined with losartan potassium in the treatment of chronic glomerulonephritis
por: Feng, Pan-Feng, et al.
Publicado: (2022)

DoE-Based Design of a Simple but Efficient Preparation Method for a Non-Effervescent Gastro-Retentive Floating Tablet Containing Metformin HCl
por: Kim, Byungsuk, et al.
Publicado: (2021)

Formulation Design and Optimization of Fast Disintegrating Lorazepam Tablets by Effervescent Method
por: Shirsand, S. B., et al.
Publicado: (2010)

Ghatti gum-base graft copolymer: a plausible platform for pH-controlled delivery of antidiabetic drugs
por: Bhosale, Rohit R., et al.
Publicado: (2021)

Stability-indicating Reversed-phase Liquid Chromatographic Method for Simultaneous Determination of Losartan Potassium and Ramipril in Tablets
por: Kollipara, S., et al.
Publicado: (2012)

Effervescing Powders
por: Maisch, Jno. M.
Publicado: (1857)

Effervescent Salts
por: Pickerill, G. W.
Publicado: (1890)

Comparative bioavailability studies of citric acid and malonic acid based aspirin effervescent tablets
por: Gauniya, Anju, et al.
Publicado: (2010)

Simultaneous Estimation of Escitalopram and Clonazepam in Tablet Dosage Forms Using HPLC-DAD Method and Optimization of Chromatographic Conditions by Box-Behnken Design
por: Foudah, Ahmed I., et al.
Publicado: (2022)

Losartan potassium loaded sustained release matrix tablets: Influence of various hydrophilic and hydrophobic polymers on drug release behaviour
por: Vohra, D. D., et al.
Publicado: (2012)

A Review on the Main Phytoconstituents, Traditional Uses, Inventions, and Patent Literature of Gum Arabic Emphasizing Acacia seyal
por: Ashour, Mohamed A., et al.
Publicado: (2022)

The Clinical Effects of Metronidazole Vaginal Effervescent Tablets Combined with Kushen Suppository in the Treatment of Trichomonas Vaginitis
por: Zhang, Hongxia, et al.
Publicado: (2022)

Role of various natural, synthetic and semi-synthetic polymers on drug release kinetics of losartan potassium oral controlled release tablets
por: Jayasree, J., et al.
Publicado: (2014)

A Green High-Performance Thin-Layer Chromatography Method for the Determination of Caffeine in Commercial Energy Drinks and Formulations
por: Foudah, Ahmed I., et al.
Publicado: (2022)

Smart Nanocarriers as an Emerging Platform for Cancer Therapy: A Review
por: Kenchegowda, Madhuchandra, et al.
Publicado: (2021)

Solubility Data of the Bioactive Compound Piperine in (Transcutol + Water) Mixtures: Computational Modeling, Hansen Solubility Parameters and Mixing Thermodynamic Parameters
por: Shakeel, Faiyaz, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vj7bml5j5vggf3lhu2hbto4eti