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Microwave Heating Promotes the S-Alkylation of Aziridine Catalyzed by Molecular Sieves: A Post-Synthetic Approach to Lanthionine-Containing Peptides

Aziridine derivatives involved in nucleophilic ring-opening reactions have attracted great interest, since they allow the preparation of biologically active molecules. A chemoselective and mild procedure to convert a peptide cysteine residue into lanthionine via S-alkylation on aziridine substrates...

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Detalles Bibliográficos
Autores principales: Verdoliva, Valentina, Digilio, Giuseppe, Saviano, Michele, De Luca, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538954/
https://www.ncbi.nlm.nih.gov/pubmed/34684715
http://dx.doi.org/10.3390/molecules26206135